The isoelectric point of sheep oxyhaemoglobin determined by titration curves with the glass electrode
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Protolytic equilibria of doxorubicin as determined by isoelectric focusing and 'electrophoretic titration curves'.
Doxorubicin (AdriamycinR) and the related compound daunorubicin (Daunomycin) are antibiotics of the anthracycline group [l] with cytotoxic and antimitotic activity [2]. Their clinical uses in the treatment of acute leukemia and solid tumors have been reviewed [3-51. Their biological activity is linked to the formation of an intercalative complex with DNA [6-S] with concomitant i~libition of bot...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1931
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1931.sp002736